N-(3-Methylenecyclobutyl)-carbamic acid phenylmethyl ester - Names and Identifiers
N-(3-Methylenecyclobutyl)-carbamic acid phenylmethyl ester - Physico-chemical Properties
Molecular Formula | C13H15NO2
|
Molar Mass | 217.26 |
Density | 1.12±0.1 g/cm3(Predicted) |
Boling Point | 358.2±32.0 °C(Predicted) |
pKa | 12.01±0.20(Predicted) |
Storage Condition | Room Temprature |
N-(3-Methylenecyclobutyl)-carbamic acid phenylmethyl ester - Introduction
N-(Benzyloxycarbonyl)-3-methylenecyclobutylamine, chemical formula C12H16N2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
N-(Benzyloxycarbonyl)-3-methylenecyclobutylamine is a colorless to slightly yellow solid. It has a certain solubility, can be dissolved in ethanol, ether and chloroform and other solvents. The melting point of this compound is about 95-98°C.
Use:
N-(benzyloxycarbonyl)-3-methylenecyclobutylamine is a commonly used reagent in organic synthesis, which can be used to synthesize compounds and drugs. It can be used as condensing agent, amine agent and dehydrating agent.
Preparation Method:
N-(Benzyloxycarbonyl)-3-methylenecyclobutylamine can be prepared by the following steps:
1. Benzylamine reacts with formaldehyde to generate N-benzyl formaldehyde amine.
2. Under alkaline conditions, N-benzylcarbaldehyde amine is reacted with cyclobutanone to obtain N-(benzyloxycarbonyl)-3-methylene cyclobutylamine.
Safety Information:
N-(benzyloxycarbonyl)-3-methylenecyclobutylamine requires the following precautions during use and storage:
1. The compound may cause irritation to the human body, and skin contact and inhalation should be avoided. Wear appropriate personal protective equipment such as lab gloves, protective glasses, etc.
2. Store away from fire and oxidant, maintain a well-ventilated environment. Avoid contact with acid, alkali and other substances to prevent dangerous reactions.
3. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
4. in the use or disposal of the compound, should comply with the appropriate safety procedures and regulatory requirements.
Last Update:2024-04-09 19:05:46